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TitleCrystal structure of human dihydroorotate dehydrogenase (DHODH) with 18XYW at 1.86 A resolution
Journal, issue, pagesTo Be Published
Publish dateMay 1, 2015 (structure data deposition date)
AuthorsHuang, J. / Wu, D. / Ouyang, P. / Lu, W. / Pu, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.86 Å
Structure data

PDB-4zl1:
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18X at 1.86 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals

ChemComp-ORO:
OROTIC ACID

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-18X:
methyl (2Z)-cyano[3-(3-fluorobiphenyl-4-yl)-4-oxo-1,3-thiazolidin-2-ylidene]acetate

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / inhibitor / complex / OXIDOREDUCTASE / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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