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TitleThe Discovery of BMS-986164, a Potent, Selective and Orally Efficacious CK1d/e/a Inhibitor from Pyrazolo-Piperazine Chemotype
Journal, issue, pagesTo Be Published
Publish dateApr 6, 2023 (structure data deposition date)
AuthorsVelaparthi, U. / Selvakumar, K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.45 Å
Structure data

PDB-8izc:
Human CK1 Delta Kinase structure bound to Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-SO4:
SULFATE ION


ChemComp, No image

ChemComp-S93:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/INHIBITOR / CK1 / kinase / inhibitor / HYDROLASE / HYDROLASE-INHIBITOR complex

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