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Structure paper

TitleThe synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells
Journal, issue, pagesTo Be Published
Publish dateMay 18, 2020 (structure data deposition date)
AuthorsBader, A. / Ewert, W. / Knoelker, H.-J. / Preller, M. / Tsiavaliaris, G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-6z2s:
Crystal structure of adhibin analogue-bound myosin-2
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-Q5Q:
3,6-dibromo-1-(hydroxymethyl)carbazole

ChemComp-AD9:
ADP METAVANADATE

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • dictyostelium discoideum (eukaryote)
KeywordsMOTOR PROTEIN / myosin / inhibitor / adhibin analogue / carbazole / pre-powerstroke state / hydrolase

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