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TitleCrystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-076
Journal, issue, pagesTo Be Published
Publish dateMay 7, 2021 (structure data deposition date)
AuthorsChan, A. / Karim, R. / Schonbrunn, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.2 Å
Structure data

PDB-7mr8:
Crystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-076
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-ZNJ:
N-{3-[(2-{3-fluoro-4-[(piperidin-4-yl)carbamoyl]anilino}-5-methylpyrimidin-4-yl)amino]-5-[(2-methylpropane-2-sulfonyl)amino]benzoyl}-L-glutamic acid

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / Bromosporine / BRD4 / BRD / BET

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