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TitleFailure of artesunate-mefloquine combination therapy for uncompli-cated Plasmodium falciparum malaria in southern Cambodia.
Journal, issue, pagesMalar. J., Vol. 2009, 8, 10, Page 8-10, Year 2009
Publish dateNov 5, 2021 (structure data deposition date)
AuthorsRogers, W.O. / Wongsrichanalai, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.78 Å
Structure data

PDB-7sqm:
Discovery and Preclinical Pharmacology of INE963, A Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cure in Uncomplicated Malaria
Method: X-RAY DIFFRACTION / Resolution: 1.78 Å

Chemicals

ChemComp-A5G:
1-[(4S)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amine

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsANTIVIRAL PROTEIN / imidazothiadiazole / antimalarial / single-dose cure / fast-acting / malaria

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