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Structure paper

TitleStructures and mechanisms of U6 snRNA m6A modification by METTL16
Journal, issue, pagesTo Be Published
Publish dateMar 19, 2025 (structure data deposition date)
AuthorsJu J / Tomita K
External linksSearch PubMed
MethodsEM (single particle) / X-ray diffraction
Resolution2.795 - 3.4 Å
Structure data

63833

9u47

EMDB-63833, PDB-9u47:
Cryo-EM structure of spMETTL16 in complex with U6 snRNA_delta17
Method: EM (single particle) / Resolution: 3.4 Å

63834

9u48

EMDB-63834, PDB-9u48:
Cryo-EM structure of spMETTL16 in complex with U6 snRNA and SAM
Method: EM (single particle) / Resolution: 2.99 Å

PDB-9m86:
Crystal structure of SpMETTL16 kinase associated 1 domain in complex with U6 snRNA internal stem loop
Method: X-RAY DIFFRACTION / Resolution: 2.795 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • schizosaccharomyces pombe (fission yeast)
KeywordsTRANSFERASE/RNA / m6A methyltransferase / U6 snRNA / protein-RNA complex / splicing / TRANSFERASE / TRANSFERASE-RNA complex

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