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Structure paper

TitleCrystal structure of activated c-KIT in complex with compound
Journal, issue, pagesTo Be Published
Publish dateNov 26, 2018 (structure data deposition date)
AuthorsWu, T.S. / Wu, S.Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.881 Å
Structure data

PDB-6itv:
Crystal structure of activated c-KIT in complex with compound
Method: X-RAY DIFFRACTION / Resolution: 1.881 Å

Chemicals

ChemComp-AWO:
N-(5-ethyl-1,2-oxazol-3-yl)-N'-[4-(2-{[6-(4-ethylpyrazin-1(4H)-yl)pyrimidin-4-yl]amino}-1,3-thiazol-5-yl)phenyl]urea

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN / Receptor tyrosine kinase DFG motif conformational control inhibitor

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