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TitleCrystallographic fragment screening against SARS-CoV-2 Nsp1 using the F2X-Entry Screen and a newly developed fragment library.
Journal, issue, pagesTo Be Published
Publish dateMay 30, 2025 (structure data deposition date)
AuthorsLennartz, F. / Wollenhaupt, J. / Oelker, M. / Froeling, P. / Mueller, U. / Deckers, A. / Grathwol, C. / Braese, S. / Jung, N. / Weiss, M.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.45 Å
Structure data

PDB-9rcz:
Structure of the N-terminal domain of non-structural protein 1 (Nsp1) from SARS-CoV-2
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / SARS-CoV-2 / Nsp1

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