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-Structure paper
Title | CryoEM structure of PS1-containing gamma-secretase in complex with MRK-560 |
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Journal, issue, pages | To Be Published |
Publish date | Aug 8, 2023 (structure data deposition date) |
Authors | Guo X / Wang Y / Zhou J / Jin C / Wang J / Jia B / Jing D / Yan C / Lei J / Zhou R / Shi Y |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 2.8 Å |
Structure data | EMDB-37106, PDB-8kco: |
Chemicals | ChemComp-NAG:
ChemComp-N60: ChemComp-PC1: ChemComp-CLR: |
Source |
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Keywords | MEMBRANE PROTEIN / Intramembrane protease / gamma-secretase / gamma-secretase inhibitor / MEMBRANE PROTEIN-HYDROLASE complex |