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Structure paper

TitleThe extracellular region of CD33 with bound sialoside analogue P22
Journal, issue, pagesTo Be Published
Publish dateNov 6, 2020 (structure data deposition date)
AuthorsBradshaw, W.J. / Katis, V.L. / Thompson, A.P. / Arrowsmith, C.H. / Edwards, A.M. / von Delft, F. / Bountra, C. / Gileadi, O.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-7aw6:
The extracellular region of CD33 with bound sialoside analogue P22
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-FVP:
2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / receptor / Siglec / Ig-like / sialic acid / Alzheimer's disease / lectin / cell surface antigen

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