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-Structure paper
Title | Single turnover covalent inhibitors for functional chaperoning of lysosomal glycoside hydrolases |
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Journal, issue, pages | To be published |
Publish date | Aug 30, 2022 (structure data deposition date) |
Authors | Bhosale, S. / Kandalkar, S. / Gilormini, P.A. / Akintola, O. / Rowland, R.J. / Adabala, P.J.P. / King, D. / Deen, M.C. / Xi, K. / Davies, G.J. ...Bhosale, S. / Kandalkar, S. / Gilormini, P.A. / Akintola, O. / Rowland, R.J. / Adabala, P.J.P. / King, D. / Deen, M.C. / Xi, K. / Davies, G.J. / Vocadlo, D.J. / Bennet, A.J. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.49 - 1.59 Å |
Structure data | PDB-8awk: PDB-8awr: PDB-8ax3: |
Chemicals | ChemComp-SO4: ChemComp-EDO: ChemComp-NAG:
ChemComp-OIW: ChemComp-NA: ChemComp-HOH:
ChemComp-OIZ:
ChemComp-OJ6: ChemComp-PEG:
ChemComp-OD0: ChemComp-GOL: ChemComp-CA: |
Source |
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Keywords | HYDROLASE / beta-glucocerebrosidase / glycoside hydrolase / inhibitor / carbasugar / pharmacological chaperone |