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TitleCrystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and Triclosan
Journal, issue, pagesTO BE PUBLISHED
Publish dateAug 13, 2013 (structure data deposition date)
AuthorsNanson, J.D. / Forwood, J.K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4m89:
Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+ and Triclosan
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-TCL:
TRICLOSAN / antifungal, antibiotic, detergent*YM

ChemComp-HOH:
WATER

Source
  • neisseria meningitidis (bacteria)
KeywordsOXIDOREDUCTASE/ANTIBIOTIC / Enoyl / acyl carrier protein / ACP / Neisseria / Inhibitor / Rossmann Fold / Reductase / NAD / Triclosan / OXIDOREDUCTASE-ANTIBIOTIC complex

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