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Structure paper

TitleSARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules
Journal, issue, pagesBiophysica, Vol. 1, Year 2021
Publish dateMar 30, 2021 (structure data deposition date)
AuthorsNguyen, A.T. / Szeto, C. / Jayasinghe, D. / Lobos, C.A. / Halim, H. / Chatzileontiadou, D.S.M. / Grant, E.J. / Gras, S.
External linksBiophysica / Search PubMed
MethodsX-ray diffraction
Resolution1.45 - 2.35 Å
Structure data

PDB-7m8s:
Crystal Structure of HLA-A*02:01 in complex with KLNDLCFTNV, an 10-mer epitope from SARS-CoV-2 Spike (S386-395)
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-7m8t:
Crystal Structure of HLA-A*11:01 in complex with NSASFSTFK, an 9-mer epitope from SARS-CoV-2 spike (S370-378)
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-7m8u:
Crystal Structure of HLA-B*35:01 in complex with IPFAMQMAY, an 9-mer epitope from SARS-CoV-2 spike (S896-904)
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsIMMUNE SYSTEM / peptide presentation / TCR / T cell / spike / immunology / epitope presentation

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