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TitleThe crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 76, Page 103-108, Year 2020
Publish dateAug 14, 2019 (structure data deposition date)
AuthorsMarcotte, D.J. / Spilker, K.A. / Wen, D. / Hesson, T. / Patterson, T.A. / Kumar, R. / Chodaparambil, J.V.
External linksActa Crystallogr. ,Sect. F / Search PubMed
MethodsX-ray diffraction
Resolution1.744 Å
Structure data

PDB-6u0k:
TTBK2 kinase domain in complex with Compound 1
Method: X-RAY DIFFRACTION / Resolution: 1.744 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-DTQ:
4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / TTBK2

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