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TitleCrystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL02134
Journal, issue, pagesTo Be Published
Publish dateAug 3, 2024 (structure data deposition date)
AuthorsPandya, V.R. / Park, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.302 Å
Structure data

PDB-9cyz:
Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL02134
Method: X-RAY DIFFRACTION / Resolution: 2.302 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-YL2:
({[6-(4-cyclopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / enzyme-ligand complex / cryptic pocket binder / isoprenoid biosynthesis

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