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Structure paper

TitleCrystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin
Journal, issue, pagesPh D Thesis
Publish dateJul 31, 2013 (structure data deposition date)
AuthorsWilliams, E. / Riesebos, E. / Vollmar, M. / Krojer, T. / Bradley, A. / Shrestha, L. / Kupinska, K. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. ...Williams, E. / Riesebos, E. / Vollmar, M. / Krojer, T. / Bradley, A. / Shrestha, L. / Kupinska, K. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Bullock, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.17 Å
Structure data

PDB-4c02:
Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-TAK:
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/ISOMERASE / TRANSFERASE-ISOMERASE COMPLEX / TRANSFERASE / DORSOMORPHIN

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