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TitleCrystal Structure of Human Haspin with an Imidazo-pyridazine ligand
Journal, issue, pagesTo be Published
Publish dateOct 30, 2008 (structure data deposition date)
AuthorsFilippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Yue, W.W. / Murray, J.W. / Pike, A.C.W. / Von Delft, F. / Arrowsmith, C.H. ...Filippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Yue, W.W. / Murray, J.W. / Pike, A.C.W. / Von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-3f2n:
Crystal Structure of Human Haspin with an Imidazo-pyridazine ligand
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-IZZ:
(2S)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Haspin / Germ cell associated 2 / haploid germ cell specific nuclear protein kinase / ATP-binding / Cell cycle / Chromatin regulator / Kinase / Magnesium / Nucleotide-binding / Nucleus / Phosphoprotein / Serine/threonine-protein kinase / Structural Genomics / Structural Genomics Consortium / SGC

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