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Structure paper

TitleStructure-Affinity Relationship Study of Bleomycins and Shble protein Using a Chemical Array
Journal, issue, pagesTo be Published
Publish dateFeb 6, 2008 (structure data deposition date)
AuthorsMiyazaki, I. / Okumura, H. / Simizu, S. / Takahashi, Y. / Kanoh, N. / Nonomura, Y. / Osada, H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-2zhp:
Crystal structure of bleomycin-binding protein from Streptoalloteichus hindustanus complexed with bleomycin derivative
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-BY6:
[(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2S,3R,4R)-5-[[(2R,3S)-1-[2-[4-[4-[3-[4-(3-aminopropylamino)butylamino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(3H-imidazol-4-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

ChemComp-CU:
COPPER (II) ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptoalloteichus hindustanus (bacteria)
KeywordsANTIBIOTIC INHIBITOR / ANTIBIOTIC RESISTANCE / bleomycin / Ligand binding protein

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