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TitleX-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547
Journal, issue, pagesTo Be Published
Publish dateOct 17, 2023 (structure data deposition date)
AuthorsHamdani, A.K. / Mesecar, A.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.86 Å
Structure data

PDB-8um5:
X-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals


ChemComp, No image

ChemComp-X3F:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / SHIP1 / INPP5D / alzheimer's disase / TREAT-AD / inhibitor

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