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TitleX-ray structure uridine phosphorylase from Vibrio cholerae in complex with new anticancer compound at 1.17 A resolution
Journal, issue, pagesTo Be Published
Publish dateJul 17, 2014 (structure data deposition date)
AuthorsProkofev, I.I. / Lashkov, A.A. / Gabdoulkhakov, A.G. / Betzel, C. / Mikhailov, A.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.13 Å
Structure data

PDB-4u2k:
X-ray structure uridine phosphorylase from Vibrio cholerae in complex with anticancer compound at 2.13 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-4WR:
1-[(2R)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-M5F:
1-[(2S)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • vibrio cholerae (bacteria)
KeywordsTRANSFERASE / Rossmann Fold

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