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Structure paper

TitleThe Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress
Journal, issue, pagesTo be Published, Year 2013
Publish dateMay 14, 2013 (structure data deposition date)
AuthorsXu, J. / Eriksson, S.E. / Cebula, M. / Sandalova, T. / Hedstrom, E. / Pader, I. / Cheng, Q. / Myers, C.R. / Nagy, P. / Hellman, U. ...Xu, J. / Eriksson, S.E. / Cebula, M. / Sandalova, T. / Hedstrom, E. / Pader, I. / Cheng, Q. / Myers, C.R. / Nagy, P. / Hellman, U. / Selivanova, G. / Lindqvist, Y. / J Arner, E.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4kpr:
Tetrameric form of rat selenoprotein thioredoxin reductase 1
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO3:
SULFITE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / Selenoprotein / mammalian thioredoxin reductase 1 / selenocysteine / FAD / Flavoprotein / Redox-active center / NADP / antioxidant

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