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TitleDerivatives of MOPS: Promising scaffolds for SARS Coronaviruses macro domain-targeted inhibition
Journal, issue, pagesFebs J., Year 2025
Publish dateJan 25, 2023 (structure data deposition date)
AuthorsOrtega-Granda, O. / Morin, B. / Alvarez, K. / Feracci, M. / Coutard, B. / Canard, B. / Ferron, F. / Rabah, N.
External linksFebs J. / Search PubMed
MethodsX-ray diffraction
Resolution1.572 Å
Structure data

PDB-8cb3:
SARS-CoV Macro domain complexed with 3-(N-morpholino)propanesulfonic acid
Method: X-RAY DIFFRACTION / Resolution: 1.572 Å

Chemicals

ChemComp-MPO:
3[N-MORPHOLINO]PROPANE SULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus
KeywordsHYDROLASE / Macro Domain / NSP3 / Structural Genomics / Marseilles Structural Genomics Program @ AFMB / MSGP

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