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TitleStructural basis of measles virus polymerase inhibition by nonnucleoside inhibitor ERDRP-0519
Journal, issue, pagesNat Commun, Vol. 16, Page 9061, Year 2025
Publish dateApr 24, 2025 (structure data deposition date)
AuthorsLiu B / Wang D / Yang G
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.48 - 2.73 Å
Structure data

70312

9oce

EMDB-70312, PDB-9oce:
2.48A cryo-EM structure of the Measles Virus L-P-C in complex with ERdRp-0519
Method: EM (single particle) / Resolution: 2.48 Å

70313

9ocf

EMDB-70313, PDB-9ocf:
2.73A cryo-EM structure of the Measles Virus L-P in complex with ERdRp-0519
Method: EM (single particle) / Resolution: 2.73 Å

Chemicals

PDB-1ef9:
THE CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE COMPLEXED WITH 2S-CARBOXYPROPYL COA

Source
  • measles virus strain edmonston-b
KeywordsVIRAL PROTEIN / TRANSFERASE / Measles virus / L protein / phosphoprotein / RNA-dependent RNA polymerase / PRNTase / GDP polyribonucleotidyl transferase / RNA capping / MTase / viral replication / C protein / ERdRp-0519

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