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Structure paper

TitleOptimal TELSAM-Target Protein Linker Character is Target Protein Dependent
Journal, issue, pagesTo Be Published
Publish dateAug 22, 2024 (structure data deposition date)
AuthorsPedroza Romo, M.J. / Averett, J.C. / Keliiliki, A. / Wilson, E.W. / Smith, C. / Hansen, D. / Averett, B. / Gonzalez, J. / Noakes, E. / Nickles, R. ...Pedroza Romo, M.J. / Averett, J.C. / Keliiliki, A. / Wilson, E.W. / Smith, C. / Hansen, D. / Averett, B. / Gonzalez, J. / Noakes, E. / Nickles, R. / Soleimani, S. / Doukov, T. / Moody, J.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.57 - 3.58 Å
Structure data

PDB-9dam:
Crystal Structure of a DARPin Fused to the 1TEL Crystallization Chaperone via a Direct Helical Fusion in a 3-Fold Crystal Form
Method: X-RAY DIFFRACTION / Resolution: 1.78 Å

PDB-9db5:
A DARPin fused to the 1TEL crystallization chaperone via a proline-alanine linker
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-9dvg:
Crystal Structure of a DARPin Fused to the 1TEL Crystallization Chaperone via a Direct Helical Fusion in a 2-Fold Crystal Form
Method: X-RAY DIFFRACTION / Resolution: 3.54 Å

PDB-9e4q:
A DARPin fused to the 3TEL crystallization chaperone via a gly-gly-gly fusion
Method: X-RAY DIFFRACTION / Resolution: 3.58 Å

Chemicals

ChemComp-ACY:
ACETIC ACID

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / TELSAM / DARPin / ETV6 / designed ankyrin repeat protein

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