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TitleCharacterisation of active site of cytochrome P450 CYP121
Journal, issue, pagesTO BE PUBLISHED
Publish dateApr 25, 2008 (structure data deposition date)
AuthorsMcLean, K.J. / Carrol, P. / Lewis, D.G. / Dunford, A.J. / Seward, H.E. / Neeli, R. / Cole, S.T. / Leys, D. / Parish, T. / Munro, A.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-3cy1:
Crystal structure of the cytochrome P450 CYP121 S279A mutant from M. tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / cytochrome P450 / CYP121 / mycobacterium tuberculosis / Heme / Iron / Metal-binding / Monooxygenase

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