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TitlePlasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-923
Journal, issue, pagesTo Be Published
Publish dateJan 12, 2020 (structure data deposition date)
AuthorsBrannigan, J.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-6tw6:
Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-923
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-NHW:
2-oxopentadecyl-CoA

ChemComp-NZE:
[(5-{4-fluoro-2-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-1H-indazol-3-yl)methyl]dimethylamine

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • plasmodium vivax sal-1 (eukaryote)
KeywordsTRANSFERASE / myristoylation / malaria / indazole inhibitor

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