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TitleAcceptance and Kinetic Resolution of alpha-Methyl-Substituted Aldehydes by Norcoclaurine Synthases
Journal, issue, pagesAcs Catalysis, Year 2019
Publish dateMay 13, 2019 (structure data deposition date)
AuthorsRoddan, R. / Gygli, G. / Sula, A. / Lichman, B.R. / Pleiss, J. / Ward, J.M. / Keep, N.H. / Hailes, H.C.
External linksAcs Catalysis / Search PubMed
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-6rp3:
Truncated Norcoclaurine synthase with reaction intermediate mimic
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-KCZ:
4-[2-[[(2~{R})-2-phenylpropyl]amino]ethyl]benzene-1,2-diol

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • thalictrum flavum subsp. glaucum (plant)
KeywordsLYASE / tetrahydroisoquinoline synthase / biotransformation

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