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TitleElucidation of multiple high-resolution states of human MutS beta by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
Journal, issue, pagesBiorxiv, Year 2024
Publish dateMar 30, 2023 (structure data deposition date)
AuthorsLee JH / Thomsen M / Daub H / Thieulin-Pardo G / Steinbacher SC / Sztyler A / Dahiya V / Neudegger T / Dominguez C / Iyer RR ...Lee JH / Thomsen M / Daub H / Thieulin-Pardo G / Steinbacher SC / Sztyler A / Dahiya V / Neudegger T / Dominguez C / Iyer RR / Wilkinson HA / Monteagudo E / Plotnikov NV / Felsenfeld DP / Haque TS / Finley M / Boudet J / Vogt TF / Prasad BC
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

16964

8olx

EMDB-16964, PDB-8olx:
MutSbeta bound to (CAG)2 DNA (canonical form)
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / PROTEROS BIOSTRUCTURES GMBH

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