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TitleHigh-resolution X-ray cocrystal structure of USP7 in complex with LX04-46
Journal, issue, pagesTo Be Published
Publish dateApr 8, 2022 (structure data deposition date)
AuthorsWen, X.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-7xhk:
High-resolution X-ray cocrystal structure of USP7 in complex with LX04-46
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-DVU:
~{N}-[[4-[6-[[1-[[2-chloranyl-4-(furan-2-yl)phenyl]methyl]-4-oxidanyl-piperidin-4-yl]methyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methyl]methanamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Inhibitor / USP7 / Complex

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