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Structure paper

TitleEstablishment and characterization of endothelial colony forming cells as a surrogate model for Fibrodysplasia Ossificans Progressiva
Journal, issue, pagesTo Be Published
Publish dateSep 7, 2017 (structure data deposition date)
AuthorsSanchez-Duffhues, G. / Orlova, V. / Benderitter, P. / Williams, E.P. / Garcia de Vinuesa, A. / Caradec, J. / van Wijhe, M. / de Boer, H. / Goumans, M.J. / Eeckhoff, M. ...Sanchez-Duffhues, G. / Orlova, V. / Benderitter, P. / Williams, E.P. / Garcia de Vinuesa, A. / Caradec, J. / van Wijhe, M. / de Boer, H. / Goumans, M.J. / Eeckhoff, M. / Morales Piga, A. / Bachiller, J. / Koolwijk, P. / Bullock, A. / Hoflack, J. / ten Dijke, P.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.56 Å
Structure data

PDB-5oy6:
Crystal structure of the ACVR1 (ALK2) kinase in complex with cyclical inhibitor OD36.
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

Chemicals

ChemComp-B4E:
cyclical inhibitor OD36

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Kinase / ALK2 / Receptor / BMP / Structural Genomics / Structural Genomics Consortium / SGC

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