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Structure paper

TitleStructural comparison of human and malarial purine nucleoside phosphorylases
Journal, issue, pagesTo be Published
Publish dateDec 10, 2003 (structure data deposition date)
AuthorsShi, W. / Lewandowicz, A. / Tyler, P.C. / Furneaux, R.H. / Almo, S.C. / Schramm, V.L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 - 2.3 Å
Structure data

PDB-1rsz:
Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1rt9:
Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-DIH:
7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

ChemComp-HOH:
WATER

ChemComp-IMH:
1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL / inhibitor*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PNP / transition-state analogue / transition state analogue

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