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Structure paper

TitleCrystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA
Journal, issue, pagesTo Be Published
Publish dateMar 20, 2023 (structure data deposition date)
AuthorsJung, H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.163 - 2.784 Å
Structure data

PDB-8gkr:
Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA
Method: X-RAY DIFFRACTION / Resolution: 2.784 Å

PDB-8gml:
Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG
Method: X-RAY DIFFRACTION / Resolution: 2.567 Å

PDB-8ski:
Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across HX
Method: X-RAY DIFFRACTION / Resolution: 2.163 Å

Chemicals

ChemComp-B7P:
2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / DNA damage / DNA replication / translesion synthesis / TRANSFERASE-DNA complex / anti-cancer / 5-FU

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