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Structure paper

TitleThe Structure of MT189-Tubulin Complex Provides Insights into Drug Design
Journal, issue, pagesLett. Drug Des. Discovery, Year 2019
Publish dateMay 21, 2018 (structure data deposition date)
AuthorsLi, Z.P. / Ma, L.L. / Wu, C.Y. / Meng, T. / Ma, L.P. / Zheng, W. / Yu, Y. / Chen, Q. / Yang, J.L. / Shen, J.G.
External linksLett. Drug Des. Discovery / Search PubMed
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-5zxh:
The structure of MT189-tubulin complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-9LX:
2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • sus scrofa (pig)
  • bos taurus (domestic cattle)
  • rattus norvegicus (Norway rat)
  • gallus gallus (chicken)
KeywordsSTRUCTURAL PROTEIN / tubulin complex

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