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TitleStructural basis for maintenance of unmethylated CpG elements by the CXXC domain of MLL and its critical contributions to MLL-AF9 immortalization activity
Journal, issue, pagesTo be Published
Publish dateDec 13, 2007 (structure data deposition date)
AuthorsCierpicki, T. / Riesbeck, L.E. / Grembecka, J. / Lukasik, S.M. / Omonkowska, M. / Shultis, D. / Zeleznik-Le, N.J. / Bushweller, J.H.
External linksSearch PubMed
MethodsNMR (solution)
Structure data

PDB-2jyi:
Solution structure of MLL CXXC domain
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PROTEIN / CXXC domain / MLL / Alternative splicing / Bromodomain / Chromosomal rearrangement / DNA-binding / Metal-binding / Nucleus / Phosphoprotein / Polymorphism / Proto-oncogene / Transcription regulation / Ubl conjugation / Zinc / Zinc-finger

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