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TitleCrystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
Journal, issue, pagesTO BE PUBLISHED
Publish dateJul 12, 2011 (structure data deposition date)
AuthorsFilippakopoulos, P. / Picaud, S. / Felletar, I. / Hewings, S.D. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Conway, S.J. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.68 Å
Structure data

PDB-3svg:
Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ODR:
(1R)-1-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxyphenyl]ethanol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsUNKNOWN FUNCTION / Isoxazole / Bromodomain / Structural Genomics / Structural Genomics Consortium / SGC

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