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Structure paper

TitleA new class of FGFR1 inhibitors
Journal, issue, pagesTo Be Published
Publish dateJan 5, 2018 (structure data deposition date)
AuthorsKalyukina, M. / Yosaatmadja, Y. / Patterson, A.V. / Smaill, J.B. / Squire, C.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-6c1o:
FGFR1 kinase domain complexed with FIIN-1
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-MK9:
N-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)prop-2-enamide

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/Transferase inhibitor / Kinase / Transferase-Transferase inhibitor complex

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