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TitleCrystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper
Journal, issue, pagesTo be Published
Publish dateOct 22, 2014 (structure data deposition date)
AuthorsJohnstone, S. / Sudom, A. / Liu, J. / Walker, N.P. / Wang, Z.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-4rmz:
Crystal Structure of IRAK-4
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-T20:
3-nitro-N-[1-phenyl-5-(piperidin-1-ylmethyl)-1H-benzimidazol-2-yl]benzamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / serine/threonine protein kinase / transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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