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TitleN174 Physically and Chemically Stabilizes the Endonuclease Reaction of APE1
Journal, issue, pagesTo Be Published
Publish dateSep 20, 2024 (structure data deposition date)
AuthorsDeHart, K.D. / Hoitsma, N.M. / Thompson, S.H. / Freudenthal, B.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-9dp1:
APE1 N174A Substrate Complex with Abasic DNA
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / APE1 / APEX1 / Endonuclease / DNA Repair / HYDROLASE-DNA complex

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