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TitleSmall-molecule scaffolds for Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) inhibitors identified by high-throughput screening and defined by X-ray crystallography
Journal, issue, pagesTo be Published
Publish dateJan 28, 2011 (structure data deposition date)
AuthorsReddy, M.C.M. / Bruning, J.B. / Thurman, C. / Sacchettini, J.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.29 Å
Structure data

PDB-3qja:
Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form
Method: X-RAY DIFFRACTION / Resolution: 1.29 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsLYASE / Indole-3-glycerol phosphate synthase / Structural Genomics / TB Structural Genomics Consortium / TBSGC

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