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Structure paper

TitleX-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a urea based inhibitor PSMA 1027
Journal, issue, pagesTo Be Published
Publish dateJun 2, 2017 (structure data deposition date)
AuthorsNovakova, Z. / Barinka, C. / Motlova, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.53 Å
Structure data

PDB-5o5u:
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a urea based inhibitor PSMA 1027
Method: X-RAY DIFFRACTION / Resolution: 1.53 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-9LZ:
(2~{S})-2-[[(2~{S})-6-[[(2~{S})-2-[[4-[[[(2~{S})-2-[[(2~{R})-2-[(6-fluoranylpyridin-3-yl)carbonylamino]-3-sulfo-propanoyl]amino]-3-sulfo-propanoyl]amino]methyl]phenyl]carbonylamino]-3-naphthalen-2-yl-propanoyl]amino]-1-oxidanyl-1-oxidanylidene-hexan-2-yl]carbamoylamino]pentanedioic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / glutamate carboxypeptidase II (GCPII); NAALADase; prostate-specific membrane antigen; urea based inhibitor

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