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Titlebeta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids
Journal, issue, pagesto be published
Publish dateDec 12, 2021 (structure data deposition date)
AuthorsLiu, H. / Panjikar, S. / Futamura, Y. / Shao, N. / Osada, H. / Zou, H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.86 Å
Structure data

PDB-7t5j:
Crystal Structure of Strictosidine Synthase in complex with S-IPA (2-(1H-indol-3-yl) propan-1-amine)
Method: X-RAY DIFFRACTION / Resolution: 2.86 Å

Chemicals

ChemComp-XLJ:
(2S)-2-(1H-indol-3-yl)propan-1-amine

ChemComp-HOH:
WATER

Source
  • rauvolfia serpentina (serpentwood)
KeywordsLYASE / ALKALOID METABOLISM / SIX BLADED BETA PROPELLER FOLD / STR1 / VACUOLE / SYNTHASE / GLYCOPROTEIN

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