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Structure paper

TitleProteasome-associated autoinflammatory syndromes: the impact of mutations in proteasome subunits on particle assembly, structure and activity
Journal, issue, pagesto be published
Publish dateFeb 28, 2025 (structure data deposition date)
AuthorsHuber, E.M. / Heinemeyer, W. / Groll, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-9qb4:
Yeast 20S proteasome mutant: beta5_T3M in complex with Carfilzomib
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • synthetic construct (others)
KeywordsHYDROLASE / Proteasome / Proteasome Associated Autoinflammatory Syndromes / Mutation / Assembly / Maturation

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