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TitleHuman farnesyl diphosphate complexed with clinical inhibitor risedronate
Journal, issue, pagesTo be Published
Publish dateFeb 1, 2005 (structure data deposition date)
AuthorsKavanagh, K.L. / Guo, K. / Oppermann, U.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1yq7:
Human farnesyl diphosphate synthase complexed with risedronate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-RIS:
1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / isoprenoid pathway / cholesterol biosynthesis / bisphosphonate inhibitor / Structural Genomics / Structural Genomics Consortium / SGC

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