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Structure paper

TitleComprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
Journal, issue, pagesTo Be Published
Publish dateSep 6, 2019 (structure data deposition date)
AuthorsGao, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.99998872297 - 3.00081756367 Å
Structure data

PDB-6u90:
Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA
Method: X-RAY DIFFRACTION / Resolution: 3.00081756367 Å

PDB-6u91:
Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with CpGpT DNA
Method: X-RAY DIFFRACTION / Resolution: 2.99998872297 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTransferase/DNA / DNMT3B / DNMT3L / DNA methylation / Methyltransferase / transferase-DNA complex / TRANSFERASE

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