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Author
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IF

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Structure paper

TitleNMR Molecular Replacement, NMR2
Journal, issue, pagesTo Be Published
Publish dateJun 19, 2015 (structure data deposition date)
AuthorsOrts, J. / Waelti, M.A. / Marsh, M. / Vera, L. / Gossert, A.D. / Guentert, P. / Riek, R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.146 Å
Structure data

PDB-5c5a:
Crystal Structure of HDM2 in complex with Nutlin-3a
Method: X-RAY DIFFRACTION / Resolution: 1.146 Å

Chemicals

ChemComp-NUT:
4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-IOD:
IODIDE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / Drug Design / HDM2 / complex structure

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