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Structure paper

TitleCrystal Structure of JMJD2A Complexed with Inhibitor
Journal, issue, pagesTo be Published
Publish dateMay 6, 2011 (structure data deposition date)
AuthorsKing, O.N.F. / Maloney, D.J. / Tumber, A. / Rai, G. / Jadhav, A. / Clifton, I.J. / Heightman, T.D. / Simeonov, A. / McDonough, M.A. / Schofield, C.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.251 - 2.33 Å
Structure data

PDB-3rvh:
Crystal Structure of JMJD2A Complexed with Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.251 Å

PDB-4gd4:
Crystal Structure of JMJD2A Complexed with Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-HQ2:
8-hydroxy-3-(piperazin-1-yl)quinoline-5-carboxylic acid

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-0WS:
2-(1H-pyrazol-3-yl)pyridine-4-carboxylic acid

Source
  • homo sapiens (human)
KeywordsOxidoreductase/Oxidoreductase Inhibitor / Oxidoreductase / jmjC Domain / Chromatin Regulator / Dioxygenase / Transcription / Iron / 2-oxoglutarate / alpha-ketoglutarate / Demethylation / Nucleus / Oxidoreductase-Oxidoreductase Inhibitor complex / Structural Genomics / Structural Genomics Consortium / SGC

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