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Structure paper

TitleStructures and neutralizing mechanisms of camel nanobodies targeting the receptor-binding domain of MERS-CoV spike glycoprotein
Journal, issue, pagesTo Be Published
Publish dateFeb 19, 2023 (structure data deposition date)
AuthorsTian L / Wang R / Zhang L / Wang X
External linksSearch PubMed
MethodsEM (single particle) / X-ray diffraction
Resolution2.5 - 3.21 Å
Structure data

35422

8ifn

EMDB-35422, PDB-8ifn:
MERS-CoV spike trimer in complex with nanobody VHH-T148
Method: EM (single particle) / Resolution: 2.81 Å

PDB-8ido:
Crystal structure of nanobody VHH-T148 with MERS-CoV RBD
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-8iee:
Crystal structure of nanobody VHH-31 with MERS-CoV RBD
Method: X-RAY DIFFRACTION / Resolution: 3.21 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • middle east respiratory syndrome-related coronavirus
  • camelus dromedarius (Arabian camel)
KeywordsVIRAL PROTEIN / MERS-CoV / nanobody / VIRAL PROTEIN-IMMUNE SYSTEM complex

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