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Structure paper

TitleSwitching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma
Journal, issue, pagesto be published
Publish dateJan 12, 2023 (structure data deposition date)
AuthorsCazzanelli, G. / Dalle Vedove, A. / Broso, F. / Burigotto, M. / Aiello, G. / Ruzzene, M. / Tiberi, L. / Fava, L. / Quattrone, A. / Lolli, G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 - 2.05 Å
Structure data

PDB-8c6l:
Human protein kinase CK2 alpha in complex with CK2-TN01
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-8c6m:
Human protein kinase CK2 alpha in complex with CK2-TN02
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-8c6n:
Human protein kinase CK2 alpha in complex with CK2-TN03
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL


ChemComp, No image

ChemComp-TO6:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER


ChemComp, No image

ChemComp-TNO:
Unknown entry


ChemComp, No image

ChemComp-TN0:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase domain

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