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Structure paper

TitleCrystal Structure of Cruzain bound to WRR-204
Journal, issue, pagesTo be Published
Publish dateApr 26, 2000 (structure data deposition date)
AuthorsBrinen, L.S. / Gillmor, S.A. / Fletterick, R.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1ewo:
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-204
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-VSC:
N-[N'-BENZYLOXYCARBONYL-PHENYLALANINYL]-3-AMINO-5-PHENYL-PENTANE-1-SULFONIC ACID PHENYL ESTER

ChemComp-HOH:
WATER

Source
  • trypanosoma cruzi (eukaryote)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / cysteine protease / drug design / covalent inhibitor / cruzipain / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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