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Structure paper

TitleStructure of a native eIF2-eIF2B complex at 2.7 Angstroms resolution.
Journal, issue, pagesScience, Year 2025
Publish dateDec 27, 2024 (structure data deposition date)
AuthorsDe Miguel C / Thorkelsson SR / Wang C / Bertolotti A
External linksScience / Search PubMed
MethodsEM (single particle)
Resolution2.7 Å
Structure data

52433

9hve

EMDB-52433, PDB-9hve:
Native human eIF2-eIF2B complex
Method: EM (single particle) / Resolution: 2.7 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

Source
  • Expi293 (human)
  • homo sapiens (human)
KeywordsTRANSLATION / Phosphorylation / Eukaryotic Initiation Factor-2B / Eukaryotic Initiation Factor-2 / Translation Complex Catalytic Native

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